I play it and experiment with pickup elevation, looking for my idea of what the guitar should sound like. Most other things are good to go, or I would not have brought the guitar home.
I spent a few days setting mine up. I began by setting it up for 10's (which is what I use on my PRS with slightly shorter scale length). But, I just couldn't get 10s to feel *right* on the 25.5" scale length Strat. So, I started over and went back to 9s. Now, it is butter and feels nearly identical to my PRS (which is sporting 10s).
I probably spent the most time dialing in the pickup height. That's the one part of a setup that I just haven't mastered. I know very well how I want a guitar to *feel*. But, with a new guitar that has unfamiliar (but beautiful) pickups, I had a tough time knowing how it should *sound* with various styles of play. But, I finally nailed it, so now I just get to play!
It is SUCH a nice feeling to have my relief, action, trem height, intonation, and PU's dialed in so that now I can just jam! And, these pickups are SO creamy!